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What’s the Difference Between CBD and THC?


What’s the Difference Between CBD and THC?

In the world of marijuana, two compounds stand out for their popularity and effects: CBD (cannabidiol) and THC (tetrahydrocannabinol). They are the most recognized cannabinoids, each with unique properties, benefits, and uses. Understanding the difference between CBD and THC can help individuals make informed decisions about their health. 


In Kentucky, where marijuana remains illegal aside from limited protection under an executive order, learning about these compounds is essential for patients preparing for the state’s forthcoming medical marijuana program in 2025.


The Basics

CBD and THC share similar molecular structures, yet they affect the body differently. Both cannabinoids interact with the body's endocannabinoid system, which regulates various processes like pain, mood, and immune response. 


THC binds primarily with CB1 receptors in the brain, producing psychoactive effects, or the “high” associated with marijuana use. In contrast, CBD does not bind strongly with CB1 receptors and is non-psychoactive, meaning it doesn’t alter the mind.


Understanding these differences is important, especially for those in Kentucky who may need medical marijuana in the near future. Since medical marijuana is still under preparation, knowing the therapeutic benefits of CBD and THC can help people make educated choices when the program launches.


Psychoactive vs. Non-Psychoactive

One of the most notable differences between CBD and THC is that THC is psychoactive, while CBD is not. THC’s psychoactive effects come from its ability to activate CB1 receptors in the brain, which produces the “high” commonly associated with marijuana. This can alter mood, perception, and cognitive function. For some patients, this is helpful for managing symptoms of severe pain or trauma, but others may want to avoid these effects.


In Kentucky, where any psychoactive marijuana use is currently illegal, CBD provides a legal alternative. Since the 2018 Farm Bill, CBD derived from hemp with less than 0.3% THC has been available in Kentucky. Patients who may need stronger THC-based treatments for conditions like chronic pain or severe nausea must wait until 2025, when Kentucky’s medical marijuana program officially begins.


Medical Benefits of CBD

CBD is praised for its range of therapeutic applications without psychoactive effects, making it an attractive option for many patients. Research has shown that CBD may be helpful in managing conditions such as:


  • Chronic Pain: CBD may reduce inflammation and pain, especially for patients with arthritis or nerve pain.

  • Anxiety and Depression: Many users find relief from anxiety and mood disorders through CBD, which interacts with serotonin receptors in the brain.

  • Epilepsy: The FDA-approved drug Epidiolex contains CBD and has been shown effective for treating rare and severe types of epilepsy.

  • Sleep Disorders: CBD may improve sleep quality for those struggling with insomnia or disrupted sleep patterns.


In Kentucky, CBD products are available in a variety of forms, including oils, tinctures, and topical creams. For now, these products are the only form of marijuana legally available for medical use in the state. When Kentucky’s medical marijuana program launches, patients with qualifying conditions will have access to both CBD and THC products under medical supervision.


Medical Benefits of THC

THC offers its own set of therapeutic benefits, particularly for conditions that may not respond to CBD alone. Some potential uses of THC include:


  • Pain Relief: THC is effective in managing severe pain, particularly in cases of cancer, neuropathy, or post-surgical pain.

  • Appetite Stimulation: Known for causing the “munchies,” THC can be beneficial for patients undergoing treatments like chemotherapy, which often reduce appetite.

  • Nausea and Vomiting Relief: THC has been shown to reduce nausea and vomiting, making it ideal for patients undergoing chemotherapy or those with chronic gastrointestinal disorders.

  • Muscle Spasticity and Neurological Disorders: THC can reduce muscle spasms, making it a viable option for patients with multiple sclerosis or spinal injuries.


In Kentucky, THC remains illegal outside of a limited executive order. Starting in 2025, Kentucky patients with qualifying medical conditions will be able to access medical marijuana products that contain THC, with a maximum possession limit of 8 ounces. This development reflects a significant shift in state policy and provides an option for patients who require THC for effective symptom management.


Legal Status of CBD and THC in Kentucky

While CBD derived from hemp is legal at the federal level and widely available in Kentucky, THC and marijuana products remain illegal in the state. The only exception is an executive order signed by Governor Andy Beshear, allowing Kentuckians with certain medical conditions to possess small amounts of marijuana purchased legally out of state. Under the executive order, patients may avoid prosecution if they can present proof of a qualifying medical condition and a receipt showing the purchase occurred in a legal state.


Kentucky’s medical marijuana program is set to begin on January 1, 2025. It will allow patients with qualifying conditions to purchase and possess medical marijuana within state lines, finally providing a legal pathway to obtain THC-based products for those who need them. Recreational marijuana will not be part of this program, so only patients with valid medical needs and certifications will have access.


Preparing for Kentucky’s Medical Marijuana Program in 2025

As Kentucky approaches the launch of its medical marijuana program, patients and caregivers should begin learning about qualifying conditions and the process of obtaining a medical marijuana card. 


Although specific regulations and requirements will be outlined closer to the program’s start date, understanding the potential benefits of CBD and THC now can help individuals make informed decisions about their health. For Kentucky residents navigating a state where marijuana laws are slowly evolving, understanding the difference between CBD and THC is crucial. 


While CBD products are currently available, they may not be sufficient for everyone, especially for patients with severe pain, nausea, or muscle spasms who may benefit from THC. When Kentucky’s medical marijuana program launches in 2025, qualified patients will have the opportunity to legally obtain and use THC-based products to manage their conditions. 


Until then, Kentucky’s executive order provides limited legal protection for individuals who meet certain criteria, but it’s essential to understand the specific requirements and risks. Obtaining a medical marijuana card once the program is available will be the best way to ensure safe, legal access to effective treatment options tailored to individual health needs. 


In short, for Kentuckians seeking relief through medical marijuana, knowledge is power. Educating yourself now about the therapeutic benefits of CBD and THC, as well as Kentucky’s upcoming medical marijuana program, will empower you to make the best choices for your health and well-being in the years to come.


Get Ready for Medical Marijuana in Kentucky

Medical marijuana will be legal in Kentucky in 2025, and we will be seeing patients soon! Stay tuned for more information about pre-booking appointments and our grand opening.


You'll meet with your doctor at either our Louisville or Lexington office, and together, you'll discuss your qualifying condition.


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